Member
Takahiro NAKAMA
Project Assistant Professor
Department of Chemistry,
The University of Tokyo,
Profile
| 2015. 3 | B.S. The University of Tokyo |
| 2017. 3 | M.S. The University of Tokyo |
| 2018. 9-11 | Visiting Student, M. Famulok lab., University of Bonn, Bonn, Germany |
| 2020. 3 | Ph.D. of Science, The University of Tokyo |
| 2020. 4 | Project Assistant Professor, The University of Tokyo |
Paper
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"Physical Isolation of Single Protein Molecules within Well-Defined Coordination Cages to Enhance Their Stability"
R. Ebihara, T. Nakama, K. Morishima, M. Yagi-Utsumi, M. Sugiyama, D. Fujita, S. Sato, M. Fujita
Angew. Chem. Int. Ed. 2024, Accepted, .
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"Organic solvent-induced structural changes in a protein confined in a giant coordination cage"
H. Tamura, T. Nakama, A. Rossen, H. Ishikita, M. Fujita
Chem. Lett. 2024, 53, upae101.
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"Metal-dependent activity control of a compact-sized 8–17 DNAzyme based on metal-mediated unnatural base pairing"
Y. Takezawa, L. Hu, T. Nakama, M. Shionoya
Chem. Commun. 2024, 60, 288–291.
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"Metal-mediated DNA strand displacement and molecular device operations based on base-pair switching of 5-hydroxyuracil nucleobases"
Y. Takezawa, K. Mori, W.-E. Huang, K. Nishiyama, T. Xing, T. Nakama, M. Shionoya
Nat. Commun. 2023, 14, 4759.
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"Hysteresis behavior in the unfolding/refolding processes of a protein trapped in metallo-cages"
T. Nakama, A. Rossen, R. Ebihara, M. Yagi-Utsumi, D. Fujita, K. kato, S. Sato, M. Fujita
Chem. Sci. 2023, 14, 2910–2914.
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"Protein stabilization and refolding in a gigantic self-assembled cage"
D. Fujita, R. Suzuki, Y. Fujii, M. Yamada, T. Nakama, A. Matsugami, F. Hayashi, J.-K. Weng, M. Yagi-Utsumi, M. Fujita
Chem 2021, 7, 2672-2683.
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"Site-specific polymerase incorporation of consecutive ligand-containing nucleotides for multiple metal-mediated base pairing"
T. Nakama, Y. Takezawa, M. Shionoya
Chem. Commun. 2021, 57, 1392-1395.
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"Sharp Switching of DNAzyme Activity through the Formation of a Cu(II)‐Mediated Carboxyimidazole Base Pair"
Y. Takezawa, L. Hu, T. Nakama, M. Shionoya
Angew. Chem. Int. Ed. 2020, 59, 21488-21492.
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"Allosteric Regulation of DNAzyme Activities through Intrastrand Transformation Induced by Cu(II)-Mediated Artificial Base Pairing"
T. Nakama, Y. Takezawa, D. Sasaki, M. Shionoya
J. Am. Chem. Soc. 2020, 142, 10153-10162.
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"Enzymatic Synthesis of Cu(II)-responsive Deoxyribozymes through Polymerase Incorporation of Artificial Ligand-type Nucleotides"
Y. Takezawa, T. Nakama, M. Shionoya
J. Am. Chem. Soc. 2019, 141, 19342-19350.
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"Metal-responsive structural transformation between artificial DNA duplexes and three-way junctions"
Y. Takezawa, S. Yoneda, J.-L. H. A. Duprey, T. Nakama, M. Shionoya
Chem. Sci. 2016, 7, 3006-3010.
Review Articles, Books, etc.
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Bismuth─Catalyzed Redox Reactions
T. Nakama
J. Synth. Org. Chem. 2021, 79, 788–789.
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"3.4 核酸無機材料"
"Handbook of Nucleic Acids Science"Y. Takezawa, T. Nakama, M. Shionoya
Kodansha Scientific 2020, p.98–106
